Crimean-Congo haemorrhagic fever is a viral haemorrhagic fever usually transmitted by ticks. It can also be contracted through contact with viraemic animal tissues (animal tissue where the virus has entered the bloodstream) during and immediately post-slaughter of animals. CCHF outbreaks constitute a threat to public health services as the virus can lead to epidemics, has a high case fatality ratio (10-40%), potentially results in hospital and health facility outbreaks, and is difficult to prevent and treat. CCHF is endemic in all of Africa, the Balkans, the Middle East and in Asia.
The disease was first described in the Crimea in 1944 and given the name Crimean haemorrhagic fever. In 1969 it was recognized that the pathogen causing Crimean haemorrhagic fever was the same as that responsible for an illness identified in 1956 in the Congo. The linkage of the two place names resulted in the current name for the disease and the virus
Following infection by a tick bite, the incubation period of Crimean-Congo haemorrhagic fever (CCHF) is usually one to three days, with a maximum of nine days. Following contact with infected blood or tissues, the incubation period is usually five to six days, with a maximum of 13 days.
General supportive care with treatment of symptoms is the main approach to managing Crimean-Congo haemorrhagic fever (CCHF) in people. The antiviral drug ribavirin has been used to treat CCHF infection with apparent benefit. Both oral and intravenous formulations seem to be effective.
The mortality rate from CCHF is approximately 30%, with death occurring in the second week of illness. In patients who recover, improvement generally begins on the ninth or tenth day after the onset of illness.
Crimean-Congo haemorrhagic fever is a viral haemorrhagic fever usually transmitted by ticks. It can also be contracted through contact with viraemic animal tissues (animal tissue where the virus has entered the bloodstream) during and immediately post-slaughter of animals. CCHF outbreaks constitute a threat to public health services as the virus can lead to epidemics, has a high case fatality ratio (10-40%), potentially results in hospital and health facility outbreaks, and is difficult to prevent and treat. CCHF is endemic in all of Africa, the Balkans, the Middle East and in Asia.
