Research Advances by NHLBI

Improving American Indian Heart Health Through Community Research

In this video, Amanda Fretts, PhD, MPH, Jason Deen, MD, and Marie Gross, RN, MPH, discuss the continuing impact of the Strong Heart Study in American Indian communities — and encourage American Indians to get involved in clinical research. The Strong Heart Study (SHS) is a long-term study of cardiovascular disease (CVD) and its risk factors among American Indians. Figuring out how common — and how serious — CVD is among American Indians has been challenging.

Women Advancing Research Through Clinical Trials

The NHLBI is leading the way in women’s cardiovascular health research, but it is crucial that women participate in research trials to advance discovery. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Learn more: http://www.nhlbi.nih.gov Follow us on Twitter: http://www.twitter.com/nih_nhlbi Like us on Facebook: http://www.facebook.com/NHLBI

The Importance of Participating in Chronic Obstructive Pulmonary Disease (COPD) Clinical Trials

If you have chronic obstructive pulmonary disease (COPD), you might be able to participate in a clinical trial to help advance research on COPD and lung health. Watch Edwin Silverman, MD, PhD, talk about the importance of participation in clinical studies. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH).

Skeletal Muscle Mitchondrial Network of a Live Mouse

Watch a 3D rendering of a portion of the skeletal muscle mitochondrial network rotate 360 degrees. Non-white colors indicate individual mitochondria. Brian Glancy, PhD, recently demonstrated that skeletal muscle mitochondria form a highly connected network resembling that of an electrical power grid and, indeed, were capable of electrical conduction of the mitochondrial membrane potential throughout the cell. The discovery of this rapid energy distribution mechanism overturned longstanding ideas regarding diffusion as the primary energy distribution pathway in skeletal muscle.

3D Image Stack of Blood Flow in a Live Mouse

Watch this high-resolution 3D image stack of a live mouse tibialis anterior muscle that shows blood flowing in the capillaries (shown in red) embedded in the sarcolemma of muscle fibers. Brian Glancy, PhD, recently demonstrated that skeletal muscle mitochondria form a highly connected network resembling an electrical power grid and, indeed, are capable of electrical conduction of the mitochondrial membrane potential throughout the cell.

Low-field MRI system for cardiac and lung imaging

Adrienne Campbell-Washburn, PhD, explains how NIH developed a low magnetic-field MRI system to improve image quality of the heart, lungs, and more. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Adrienne Campbell-Washburn is a staff scientist in the Cardiovascular Branch at NHLBI.

Sickle Cell Disease Care in the Emergency Department: Improvement Initiatives and Ongoing Research

This webinar covers current evidence-based best practices and ongoing research designed to improve the care of patients with sickle cell disease in emergency departments. The session is cosponsored by the HHS Office of Minority Health and the American College of Emergency Physicians. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH).

Genetic Therapies in Sickle Cell Disease

This webinar provides an overview of genetic therapies — what they are, how they work, and how they may be able to prevent or treat diseases. It also highlights activities of the Cure Sickle Cell Initiative, an NHLBI-led collaborative research effort to accelerate the development of genetic therapies to cure sickle cell disease. And you’ll hear a patient's perspective of participating in clinical trials and the importance of safe and widely available cures. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH).

Demonstration of the LAMPOON procedure

Jaffar M. Khan, BM, BCh, demonstrates the LAMPOON procedure and how it prevents the obstruction of blood flow in the left ventricular outflow tract. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Jaffar M. Khan is a staff clinician in the Cardiovascular Intervention Program at NHLBI.

Imaging Center for Children with Congenital Heart Disease

Congenital heart disease is the most common birth defect. Many children born with congenital heart disease will need imaging procedures to help doctors treat their specific problem. Children’s National Medical Center in Washington, DC, opened an imaging center designed for infants and children with congenital heart disease. Watch doctors from Children’s National Medical Center and NHLBI scientists discuss how this center will improve doctors’ ability to diagnose and treat children with congenital heart disease.