Science

Watch a 3D rendering of a portion of the skeletal muscle mitochondrial network rotate 360 degrees. Non-white colors indicate individual mitochondria. Brian Glancy, PhD, recently demonstrated that skeletal muscle mitochondria form a highly connected network resembling that of an electrical power grid and, indeed, were capable of electrical conduction of the mitochondrial membrane potential throughout the cell. The discovery of this rapid energy distribution mechanism overturned longstanding ideas regarding diffusion as the primary energy distribution pathway in skeletal muscle.

Watch this high-resolution 3D image stack of a live mouse tibialis anterior muscle that shows blood flowing in the capillaries (shown in red) embedded in the sarcolemma of muscle fibers. Brian Glancy, PhD, recently demonstrated that skeletal muscle mitochondria form a highly connected network resembling an electrical power grid and, indeed, are capable of electrical conduction of the mitochondrial membrane potential throughout the cell.

Adrienne Campbell-Washburn, PhD, explains how NIH developed a low magnetic-field MRI system to improve image quality of the heart, lungs, and more. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Adrienne Campbell-Washburn is a staff scientist in the Cardiovascular Branch at NHLBI.

This webinar covers current evidence-based best practices and ongoing research designed to improve the care of patients with sickle cell disease in emergency departments. The session is cosponsored by the HHS Office of Minority Health and the American College of Emergency Physicians. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH).

This webinar provides an overview of genetic therapies — what they are, how they work, and how they may be able to prevent or treat diseases. It also highlights activities of the Cure Sickle Cell Initiative, an NHLBI-led collaborative research effort to accelerate the development of genetic therapies to cure sickle cell disease. And you’ll hear a patient's perspective of participating in clinical trials and the importance of safe and widely available cures. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH).

Jaffar M. Khan, BM, BCh, demonstrates the LAMPOON procedure and how it prevents the obstruction of blood flow in the left ventricular outflow tract. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Jaffar M. Khan is a staff clinician in the Cardiovascular Intervention Program at NHLBI.

Congenital heart disease is the most common birth defect. Many children born with congenital heart disease will need imaging procedures to help doctors treat their specific problem. Children’s National Medical Center in Washington, DC, opened an imaging center designed for infants and children with congenital heart disease. Watch doctors from Children’s National Medical Center and NHLBI scientists discuss how this center will improve doctors’ ability to diagnose and treat children with congenital heart disease.

Nearly 300,000 children are born with sickle cell disease (SCD) around the world each year. Watch Michael R. Debaun, MD, MPH, discuss how the Primary Prevention of Stroke in Children with SCD in Sub-Saharan Africa II study, funded by the National Institute of Neurological Disorders and Stroke, aims to help children with sickle cell disease live stroke-free by 2025. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr.

Watch this video to see Lakshmanan Krishnamurti, MD, discuss how NHLBI brings researchers together with the shared goal of improving quality of life for patients with sickle cell disease. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Krishnamurti is Director of the Pediatric BMT Program at the Aflac Cancer and Blood Disorders Center at Children’s Healthcare of Atlanta/Emory University.

Watch this video to see Marsha J. Treadwell, PhD, discuss how pain management research funded by NHLBI helps improve quality of life for patients with sickle cell disease. This video is by the National Heart, Lung, and Blood Institute (NHLBI), part of the National Institutes of Health (NIH). Dr. Treadwell is Director of the Northern California Network of Care for Sickle Cell Disease at UCSF Benioff Children's Hospital Oakland.