2018-Feb MBBS Question Papers

Define and classify drowning.  Describe Post Mortem findings in a case of death due to drowning in a swimming pool.

2+3+5=10

WRITE SHORT NOTES ON:

5X4=20

Viscera preservation in a case of poisoning

Entry and exit wound of a  rifle bullet

Differentiate between civil and criminal negligence

Primary impact injuries

Informed consent

WRITE BRIEFLY ON:

5X2=10

Contraindications of gastric lavage

Kleptomania and Mutilomania

Magistrate’s  inquest

Chop wounds

Management of strychnine poisoning 

List the virulence factors of Yersinia Pestis.  Describe the pathogenesis of Bubonic Plague.  Add a note on the laboratory diagnosis of Plague.

2+3+5=10

WRITE SHORT NOTES ON:

5X4=20

IFAT (Indirect Immunofluorescent Antibody Test)

Classify Immunodeficiency diseases

Type IV Hypersensitivity reaction

Bacterial Endospore

Laboratory diagnosis of Streptococcal (Group A) Sore Throat

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5X2=10

Endemic Typhus

Selective Media

Morphology of Neisseria Meningitis (Meningococcus) with diagram

Immunoglobin A

Insertion Sequence

Describe the morphology and life cycle of Plasmodium vivax.  Discuss laboratory diagnosis of malaria.  What are the complications of malaria?

2+2+4+2=10

WRITE SHORT NOTES ON:

5x4=20

Giardiasis

Hydatid disease

Laboratory diagnosis of Hepatitis B

Cryptococcus neoformans

Cultivation of viruses

WRITE BRIEFLY ON:

5x2=10

Slide culture

Draw and label influenza virus

Bile stained helminthic ova

Herpes zoster

What are Dimorphic fungi?  Give two examples.

A forty year old man presented with history of persistent cough and evening rise of temperature over a period of 4 months, with associated loss of appetite and reduction in weight.  Examination revealed matted cervical lymph nodes.  An X ray chest done showed a small radiopaque focus in the apex of the upper lobe of right lung.

1. What is your diagnosis?
2. Describe in detail the pathogenesis of this disease.
3. Describe the microscopic features associated with this lesion.
4. Enumerate the complications associated with this condition.

1+4+3+2=10

WRITE SHORT NOTES ON:

5X4=20

Mechanism of wound healing by second intention

Type II hypersensitivity reaction

Characteristics of Benign and Malignant neoplasms

Laboratory investigations in a case of Hereditary spherocytosis

Pathogenesis of Septic Shock

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5X2=10

List any four types of necrosis with one example for each

Mention four inflammatory actions of Arachidonic acid metabolites

List four special stains to demonstrate amyloid

List four examples for edema due to reduced plasma osmotic pressure

Laboratory investigations in a case of Idiopathic Thrombocytopenic Purpura (ITP)

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A 65 year old man, a chronic smoker, presented with history of weight loss, low grade fever and difficulty in breathing.  He gave history of hemoptysis for last month.  X-ray chest showed enlarged Right tracheobronchial lymph nodes.  Bronchoscopy revealed a fungating growth in the right bronchus.

1. What is the probable diagnosis
2. Mention the major types (classification)
3. Give the spread of the tumour
4. What is paraneoplastic syndrome?  Give features of paraneoplastic syndrome.

1+3+2+4=10

WRITE SHORT NOTES ON:

5X4=20

Helicobacter pylori and peptic ulcer

Morphology of Myocardial Infarction

Give causes of crescent formation.  Give gross and microscopic picture of Rapidly progressive glomerulonephritis

Post necrotic cirrhosis liver

Give the microscopic picture, X-ray appearance and spread of osteogenic sarcoma                                                               

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5X2=10

Nodular Sclerosing type of Hodgkin disease

Enumerate pathogenic factors of Carcinoma cervix

CSF findings in Tuberculous Meningitis

Name four prognostic factors of breast cancer

What is the pathogenesis of Dissecting aneurysms?

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Classify β blockers.  Write their Pharmacological action, therapeutic uses and adverse effects of β blockers.

3+2+3+2=10

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5X4=20

Transdermal patch

Pharmacovigilance

Therapeutic uses of Prostaglandin Analogues

Potassium Channel Openers

Propofol

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5X2=10

Mention two examples of Cytochrome P450 induction

Mention four SSRI (Selective Serotonin Reuptake Inhibitors)

Tramadol

Articaine

Mannitol