2019-Feb MBBS Question Papers

Describe the Pathogenicity and lab diagnosis of Pulmonary tuberculosis.  Add a note on RNTCP.

3+4+3=10

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5X4=20

Hot Air Oven

Bacterial spore

Lab diagnosis of Enteric Fever

Auto immunity

Anaphylaxis

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5X2=10

Enrichment media

Structure of IgM

Tyndallization

Two Non suppurative infections caused by Streptococci

VDRL Test

Classify Organophosphates.  Mention the clinical findings in Organophosphorus Poisoning.  Describe the treatment of Organophosphorus poisoning.

2+4+4=10

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5X4=20

Doctrine of Res Ipsa Loquitur

Brainstem death

Delusion and its medicolegal importance

Medical Findings in a victim of Rape

Medical Termination of Pregnancy Act

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5X2=10

Signs and Symptoms of Lead Poisoning

Café Coronary syndrome

Superfecundation and Superfetation

Vicarious liability

Negative Autopsy 

Classify human fungus infections (Mycoses).  Write a detailed note on various types of superficial mycoses.

3+7=10

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5x4=20

Post exposure Prophylaxis in Rabies

Morphology and pathogenesis of Human Immunodeficiency Virus

Cultivation of Viruses

Life cycle and Pathogenicity of Taenia solium

Dimorphic Fungi

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5x2=10

Name two antifungal agents

MMR Vaccine

Name two Arboviral infections in India and their vectors

Morphology of influenza virus

NNN medium

A 55 year old lady presented with progressive fatigue and tiredness for last one month.  She also complained of tingling and numbness in the lower limbs.  On examination she had pallor and her tongue had a glossy appearance.

1. What is your diagnosis?
2. What is the cause for neurological symptoms in this condition?
3. What are the peripheral smear and bone marrow findings in this condition?
4. Which specific tests would you like to do to diagnose this condition?

1+2+5+2=10

WRITE SHORT NOTES ON:

5X4=20

Role of Rb gene in tumor suppression

Lab diagnosis of chronic myeloid leukemia

Pathogenesis of primary pulmonary tuberculosis

Morphology of lepromatous leprosy

Role of vasoactive amines in acute inflammation

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5X2=10

Fate of thrombus

Morphological changes in apoptosis

Variants of Reed Sternberg cell

Principle of Osmotic fragility test

List four clinical features of Klinefelter Syndrome

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An 8 year old boy came with history of puffiness of face with decreased urine output.  His urine examination revealed numerous RBCs with mild proteinuria.  Renal biopsy was performed which showed glomerular hypercellularity with neutrophils.

1. What is your diagnosis?
2. Describe the pathogenesis and laboratory findings in this condition.
3. What are the features on immunofluorescence and electron microscopy?

1+5+4=10

WRITE SHORT NOTES ON:

5X4=20

Sequence of serologic markers in acute hepatitis B infection

Light microscopic changes in the evolution of acute myocardial infarction in the first 14 days

Pathogenesis of cervical carcinoma

Discuss the different types of emphysema

Hereditary non-polyposis colorectal cancer

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5X2=10

Four differences between complete and partial mole

Enlist four major prognostic factors of carcinoma breast

Pathogenesis of Hashimoto’s Thyroiditis

Microscopic features of basal cell carcinoma

Barrett Esophagus

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Classify Anticholinergics.  Write the Pharmacological actions, uses and adverse effects of Atropine.

3+3+2+2=10

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5X4=20

Pharmacogenetics

Selective Cox-2 Inhibitors

Calcium Channel Blockers

Thiazide Diuretics

Atypical Antipsychotics

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5X2=10

What are the types of Receptors involved in Mechanism of drug action?

Write any four contraindications for the use of morphine

Name any two antiplatelet drugs and its mechanism of action

Mention any 2 nasal decongestants and its side effects

Mention any 2 oral and parenteral iron preparations and its side effects.

Write the first line and second line anti TB Drugs.  Explain the Mechanism of action, uses and adverse effects of Rifampicin.

3+2+2+3=10

WRITE SHORT NOTES ON:

5x4=20

Tetracycline

Therapeutic uses of Corticosteroids

Selective Estrogen Receptor Modulator (SERM)

Proton Pump Inhibitors

Common side effects of Anti cancer drugs

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5X2=10

Write any 4 antibiotics contraindicated in pregnancy and its effect on the foetus

Treatment of H.Pylori Infection

Mention any 4 drugs used for Hepatitis B virus infection

Name α-Glucosidase inhibitors and its side effects

Mention four therapeutic uses of Chloroquine