M.B.B.S. EXAMINATION PATHOLOGY

M.B.B.S. DEGREE EXAMINATION – JANUARY, 2014

M.B.B.S. EXAMINATION   PATHOLOGY

 (GENERAL PATHOLOGY & HAEMATOLOGY)

PAPER-I

Time : 2 Hours                                                                      Max. Marks: 40

Answer all questions

1. A male child aged 8 years presented with fever, fatigue, generalized lymphadenopathy, bone pain, petechial hemorrhages over the skin, pallor, enlarged testes and features of meningism.

1. What is the provisional diagnosis?
2. Describe blood and bone marrow picture and
3. Other investigations to confirm the diagnosis.
4. Discuss the prognosis of the same.                    (1+4+3+2=10)

WRITE SHORT NOTES ON:                                                     5x4=20

2. Etiology and pathogenesis of fat embolism
3. Mention Arachidonic acid metabolites and their role in inflammation.
4. Tabulate the differentiating features of Necrosis and Apoptosis
5. Describe the chemical nature of Amyloid
6. Describe the steps / events involved in mechanism of tumor

INVASION and METASTASIS

WRITE BRIEFLY ON:                                                              5x2=10

7. Name any four (4) pathological changes in Vitamin A deficiency
8. Name any four (4) growth factors involved in regeneration and wound healing
9. Name one (1) infectious disease and three (3) tumors caused by Epstein-Barr virus

         10) Name three (3) X-linked recessive and one (1) X-linked

                dominant disorders

         11) Name two (2) special stains for reticulocytes and two (2)

                causes of Reticulocytosis.

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