M.B.B.S. EXAMINATION PATHOLOGY (GENERAL PATHOLOGY & HAEMATOLOGY) PAPER-I

M.B.B.S. DEGREE EXAMINATION – JULY, 2013

PAPER-I

Time : 2 Hours                                                                   Max. Marks: 40

Answer all questions

1. A 35 year old male was admitted with easy fatigability, anorexia, weakness, weight loss, night sweats and dragging sensation in the abdomen due to massive splenomegaly.    His total WBC count was 2,00,000 cells / mm^3.

1. 1. What is the provisional diagnosis?
   2. Describe the blood and bone marrow picture.
   3. Describe the chromosomal abnormality of the disease
   4. Mention various phases of the disease.            1+5+2+2=10                                                                           

     WRITE SHORT NOTES ON:                                                        5x4=20

2. Free radicals
3. Phagocytosis
4. Klinefelter’s syndrome
5. Packed cell volume (PVC)
6. Healing by second intention and complications of wound  healing

WRITE BRIEFLY ON:                                                                  5x2=10

7. Characteristics of malignant cell
8. Fate of thrombus
9. Lipofuscin

10. Tuberculoid Leprosy – Microscopic picture

   11. Sago spleen