M.B.B.S. EXAMINATION PHARMACOLOGY PAPER-I

M.B.B.S. DEGREE EXAMINATION – JULY, 2013

PAPER-I

Time : 2 Hours                                                             Max. Marks : 40

Answer all questions

1. Enumerate the antipsychotics.  Explain the mechanism of

action and enumerate the adverse effects and uses of Chlorpromazine.                                                                              10

WRITE SHORT NOTES ON:                                                     5X4=20

2. Uses and adverse effects of diazepam
3. Give the comparison and contrast between tubocurarine and succinylcholine

4. Transdermal drug administration
5. Name 4 antihypertensive drugs.  Write the pharmacological basis for use in hypertension of any two of them.
6. Pharmacokinetic drug interactions

WRITE BRIEFLY ON:                                                            5X2=10

7. What is therapeutic index?  Name two drugs that have low therapeutic index.
8. Morphine is used in myocardial infection – give reason
9. Atropine is used in organophosphorus poisoning – give reason

10. Sildenafil should be avoided in patients receiving organic

       nitrates – give reason.

11. Name 2 potassium sparing diuretics and 2 loop diuretics.